Hi again,
Rodney whyte is fabulous with drugs - good one Barb. He will be able to discuss safe dosage levels re breastfeeding.

Re changing meds - this can be a minefield to get balance - if it aint broke dont fix it would be my maxim. I have been to hell and back with my family member ( as has he!) on meds that didnt work well - Valproate was used for years with him and dosages were frequently adjusted without good balance between a therapeutic dose and side effects -side effects included weight gain ( severe); lethargy ( not easy to be responsive to a baby if you are comatose much of the day); and after several years he has drug induced hepatitis from the valproate ( biopsy diagnosed)- liver count has been high for almost a year now - ALT went up to 900 ( normal is 50; still hovering around 300 - 400) so all meds were removed ( thanks gastroenterologist!) and of course severe mania/ psychosis ensued. Lithium has been a godsend - as he now cant take any antidepressants because those that arent metabilised by the liver seem to create severe side effects. On lithium he only needs a very low dose of an antipsychotic - he had to come off a very effective one due to liver metabolism - was on antipsychotic and antidepressant while on valproate. I say lithium is great -so far..moods are stable (highs and lows seem to be minimised) ; side effects are minimal in comparison to all the other cocktails he was on - the bigger the mix of drugs the more side effects ( he is already on thyroxin -your client will need thyroid level checks too).

I too find it crazy that each Dr cares for a small portion of the whole person when it comes to mental illness - dont get me started -I case manage because it seems there isnt a professional who can manage the total wellbeing or knows which drugs may affect the other bodily organs/ functions - have had psyciatrist prescribe drugs which cant be taken with poor liver function and gastros who remove psych drugs that are vital for sanity. I would trust the womans family members if they are invloved in her care and she sounds like she knows her body and how the drugs work for her (non pregnant at least). It is all so individual - not an exact science at all with psych meds.

Good luck,
Pinky


----- Original Message ----- From: "Sue Cookson" <[EMAIL PROTECTED]>
To: <[email protected]>
Sent: Wednesday, January 03, 2007 9:43 PM
Subject: Re: [ozmidwifery] birth and mental health


Thanks Pinky,
That's great information and very insightful.
I didn't know about increasing the lithium - she talked about decreasing it as it takes 6 months off lithium for her to become symptomatic. It's so hard to work through all the conflicting research and getting info from practitioners who specialise in one area only - like the psychiatrists who want to change her meds so she can breastfeed - surely we can milk bank or whatever initially to prevent baby's dehydration/ maternal sleep deprivation - the two main problems that I can see - and meantime keep her on meds that she is confident with and keep her well balanced.

Any further info or stories would be very welcome,
Sue

Hi Sue -I have vivid memories of a mum who came off lithium so she would be able to breastfeed- went into psychosis and didnt even recognise her bub. It was years ago .

According to Hale(Medications in mothers milk. 11th edition) - lithium is generally increased (dosage) during preg due to increased renal clearance . After birth, levels need to be closely monitored as mother's renal clearance drops to normal. Several cases of lithium toxicity have been reported in newborns. According to Hale, breastfeeding is not necessarily contraindicated as long as babys levels are monitored and there are no symptoms of toxcicity but other anti manic drugs such as valproate may be a better option for breastfeeding mums. Of course this depends how confident the woman is re changing meds if the lithium is effective and balanced for her.

Living with a family member on lithium ( male so not giving birth) the sad thing I have observed is that as people with mental illness become unwell they lose the insight that would tell them they were becoming unwell and so tend to blame others around them to rationalise their symptoms. I would suggest the woman and her partner/ family member give you a list of 'early warning signs' of her illness before she has her bub and that she keeps in good contact with her psychiatrist throughout pregnancy and postpartum. Home birth may be much better than hospital as she will be in familiar surroundings so will be monitored by loved ones who know her well and not treated with 'kid gloves' for what may well be 'normal' postpartum mood changes. Except of course that severe mania can happen very quickly and be very scary for everyone around to contain. What would be their plan if she became unwell? Get them to write this as they woudl a birth plan.

Pinky


----- Original Message ----- From: "Sue Cookson" <[EMAIL PROTECTED]>
To: <[email protected]>
Sent: Wednesday, January 03, 2007 6:03 PM
Subject: [ozmidwifery] birth and mental health


Hi,
Do any of you have stories relating to the use of Lexapro and Lithium (two different women) and birth - particularly homebirths.
Would appreciate any feedback re outcomes and neonatal well being.
Also how the women manage their medication both pre and post birth.

As usual there is a lot of info out thereand a lot of it conflicting,

Thanks,
Sue
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