On 5/6/05, Jim Devine <[EMAIL PROTECTED]> wrote:
> The unselfish gene
> 
> The new biology is reasserting the primacy of the whole organism - the
> individual - over the behaviour of isolated genes
> 
> Johnjoe McFadden
> Friday May 6, 2005
> The Guardian [U.K.]

--------------------

Not much new here, I'm afraid; evo. theorists have been railing
against gene-centricity etc. since George Williams 1966 classic
"Adaptation and Natural Selection".

McFadden's own preferred hypotheses are themselves extremely
controversial, as he tries to bring quantum theory as crucial to
understanding/explaining the origins of cells and a whole lot more:

"The first target in our search for the quantum-classical border
inside the cell will be a proton that is part of one of the cell's
many proteins: a single molecule of the enzyme called
beta-galactosidase. The enzyme looks rather like any other protein
inside the cell: a tightly knotted bundle of amino acid rope made up
of about 1000 amino acids. But this enzyme is currently inactive. Its
job, when it is active, is to hydrolyse (react with water) the
disaccharide milk sugar lactose, breaking into its two component bits:
glucose and galactose. However, the human host to our E. coli cell has
not drunk any milk since breakfast and it is now the middle of the
night. The enzyme has nothing to do until the next batch of lactose
arrives, along with the breakfast cereal, the next morning. Our cell
has been without food for some time now and has exhausted its
reserves. To conserve energy, it switches itself into a kind of
hibernation state called dormancy, until the lactose arrives.

Our information is that within the beta-galactosidase enzyme lies our
target proton on one of the protein's amino acids. This proton
(remember, a hydrogen nucleus) is attached to an oxygen atom within
the amino acid molecule, by a covalent bond. Our sources also tell us
that nearby lies a nitrogen atom which like the oxygen atom, is
relatively electron rich and would like to capture our target proton.
We will imagine that if our proton is supplied with enough energy then
it might escape the pull of the oxygen atom's electrons and hop onto
the nitrogen atom. In fact, we will suppose that calculations indicate
that at body temperature the surrounding thermal energy gives the
proton a 50% chance of hopping from one atom to another."

<http://www.surrey.ac.uk/qe/C11.htm>

<http://www.surrey.ac.uk/qe/>



-- 
"C'mon Mr. Krinkle, tell me why" [Primus]

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