Infected Planet
By Stan Cox, AlterNet
Posted on March 21, 2006, Printed on March 22, 2006
http://www.alternet.org/story/33703/

When Michael Crichton's first novel, "The Andromeda Strain," was published
in 1969, it was scary but also strangely reassuring. If some new disease
were to threaten humanity with a deadly pandemic, it seemed, the microbe
responsible would come from another planet. The march of medical progress
appeared to have terrestrial germs on the run.

Twenty-five years later, when Laurie Garrett published her nonfiction
bestseller, "The Coming Plague," people were waking up to the fact that our
own abused planet is perfectly capable of spawning a steady stream of new
diseases without any help from alien worlds.

Today, old familiar scourges like tuberculosis, malaria, measles, and
diarrhea -- and a newer one, AIDS -- are the world's biggest killers, but
they've been joined by a host of newcomers. Indeed, one could get the
impression that each year brings a new disease. That's because it does.

Mark Woolhouse, chair of Infectious Disease Epidemiology at the University
of Edinburgh, has counted 38 new pathogens (disease-causing biological
agents) that have moved into the human population from other animal species
in just the past 25 years. In a presentation at the annual meeting of the
American Association for the Advancement of Science last month, Woolhouse
noted that we're under assault not only from those novel species, but also
from new genetic variants of pathogens that have been with us for a long time.

A recent tally identified 1,415 disease-causing microbes in humans,
including bacteria, viruses, fungi and parasitic worms. We share fully 61
percent of those pathogens with other animal species. Of the total, 175
cause "emerging diseases" -- ones not known until recently in humans. Of
those, 75 percent came out of other animals to invade Homo sapiens.

The impact of species-jumping pathogens varies. Hendra virus moved from
fruit bats to horses in 1994 and is known to have killed a total of only
three people. Since the 1970s, the Ebola virus has incited some horrifying
outbreaks that, so far, have failed to blow up into epidemics. Influenza
viruses usually cause a lower mortality rate but hit far more people;
currently, an H5N1 "bird flu" strain threatens to break that pattern by
staging an encore of the 1918-19 killer flu pandemic that killed 50 million
to 100 million people. HIV/AIDS is both chronically widespread and deadly,
now accounting for almost a fourth of infectious disease deaths.

But have "emerging" species-jumping diseases actually been with us for
millenia, identified only when medical research achieves sufficient
precision in detecting and identifying microbes? Durland Fish, professor at
the Yale School of Public Health, says that better research is part of it,
but there still appears to be a faster rate of disease appearance these
days. He told me, "Dr. Woolhouse makes an interesting point: that 'emerging
disease' is a new concept but a very old process. Humans have always
acquired new diseases." We're being hit more frequently today than in
previous eras, he says, partly because "transportation, trade, human
population growth, and environmental change are going on at unprecedented
rates."

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