There is a SetCharFormat method to the RichEdit control. $Rich->Select ($from_here, $to_there); $Rich->SetCharFormat (-color => $flashy_pink)
Look up http://www.jeb.ca/ for tons of information and knowledge (-> Win32-GUI -> FAQ), also contains links to Aldo's documentation http://dada.perl.it/gui_docs/gui.html, or see wex.pl @ http://www.fairymails.com/perl/ for an example in action.