Salam Permias.
Saat ini saatnya PERMIAS berbicara mengenai science and technology. Saat ini saatnya PERMIAS berbicara mengenai data-data penelitian. Selain itu PERMIAS harus dapat menjadi "jembatan" bagi penelitian di Indonesia dan Amerika.
Mohon doa restu dan kami akan terus mengupdate acara ini.
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Indonesian Student in Los Angeles Scientific Meeting I
Objectives:
1. To provide a media for Indonesian students in Los Angeles to communicate and present their research topics
2. To serve as a cross-area studies discussion forum between Indonesian students
3. To promote research among indonesian students
Venue:
North Mudd Building (Geological and Planetary Science Div.), California Institute of Technology, Pasadena. Address: Northeast corner of the intersection between E. California Blvd and Wilson Ave, Pasadena. http://www.gps.caltech.edu/
Time: Saturday, Feb 23rd, 2002. 3 PM - 6 PM.
Social Event will be held following the meeting.
*Event speakers are subject to change without prior notice. A fixed schedule is available or to be determined during the event.
More info:
1. Cortino Sukotjo: [EMAIL PROTECTED], 310-592-0791
2. Danny H. Natawidjaja, [EMAIL PROTECTED]: 1-626-379-7841
3. Suprayoga Hadi: [EMAIL PROTECTED]: 1-626-278-0036
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Speakers (tentative) :
1. Sierin Lim received her Bachelor degree in Chemical Engineering with biological emphasis from University of California Los Angeles. She was a recipient of UCLA Biomedical Engineering Departmental Fellowship in 2001 and currently she is a Ph.D student in Biomedical Engineering, University of California Los Angeles, CA
Abstract:
Purification and Characterization of a Novel Proline Dehydrogenase from
Pyrobaculum aerophilum
The goal of this study is to purify and characterize a proline dehydrogenase that was identified in the soluble fraction of hyperthermophilic archaeon P. aerophilum. The enzyme was purified 503-fold to homogeneity as a monomer of 48,000. Using spectrophotometric characterization, the highest activity was measured at 85C and pH of 6.5. It had a half-life of 6 hours at 90C incubation. The N-terminal amino acid sequence matched a hypothetical protein in the yet unpublished P. aerophilum genome data bank. Further analysis suggests that the enzyme constitutes a novel enzyme and may serve as a link in the evolution of the sarcosine oxidase and proline dehydrogenase family of enzymes.
2. Paula Gunawan received her Bachelor of Science in Chemistry-Summa Cum Laude from University of Wisconsin, Madison and Master of Science in Organic Chemistry from University of California Los Angeles, CA. She was the recipient of Howard Hughes Medical Institute Fellowship , Martha Gunhild Week Scholarship, Margaret MacLean Bender Scholarship, and Evan P. Helfaer Scholarship. She is also a member of American Chemical Society and elected member of the Golden Key National Honor Society and Phi Kappa Phi.
Abstract:
PET (Positron Emission Tomography): An Overview
Nuclear medicine is the field of medical practice that involves the oral or intravenous administration of radioactive materials for use in diagnosis or therapy. However, the majority of radiopharmaceuticals available (95%) are used for diagnostic purposes. One of the powerful tools available for monitoring the pathway of these radiopharmaceuticals after being injected into our body is by utilizing PET or Positron Emission Tomograpy. By definition, PET is an analytical imaging technology developed to use compounds labeled with positron emitting radioisotopes as molecular probes to image and measure biochemical processes of mammals in vivo. It is shown to give more accurate results by 8-43%, compared to conventional tools, such as CT Scan or MRI (Magnetic Resonance Imaging). Since diagnostic accuracy is crucial in determining therapeutic effectiveness and ultimately prolonging the patient's life, PET has received considerable attention in the pharmaceutical industry. An overview of PET, as well as its applications for diagnostic purposes for various diseases, such as cancer, Alzheimer, and Parkinson, are summarized in the presentation.
3. Isabella H. Wulur received her Bachelor of Science in Biochemistry with Latin Honor-Summa Cum Laude from University of California, Los Angeles and currently she is currently a Master Candidate in Biomedical Engineering with Biomaterials and Tissue Engineering emphasis, University of California, Los Angeles. She was a recipient of Honorable Mention Poster Presentation - Southern California Biomedical Engineering & activities: Student Symposium, University of California, Los Angeles, UCLA Dean's Special Graduate Student Researcher Fellowship, Highest Honor - UCLA Biochemistry Department, Coca-cola Research Scholarship, University Honors Program Residential Fellowship.
Abstract:
4. Cortino Sukotjo received his Dental Degree with honors from Faculty of Dentistry, Padjadjaran University, Bandung, Indonesia. Currently he is a Ph.D candidate in Oral Biology Department, School of Dentistry, University of California, Los Angeles. He was the recipient of Morita Award, IADR, Chiba, Japan and presently he is a recipient of Strauman Fellowship Award from Harvard School of Dental Medicine, Boston, Massachusetts and a finalist for Arthur Frechette Award, AADR, San Diego, CA. He is a member of International Association of Dental Research [IADR], American College of Prosthodontics, and American Academy of Osseointegration.
Abstract:
Wit 3.0 Encodes Cytoplasmic Molecules Facilitating Oral Mucosa Wound Contraction
Adult soft tissue wound often heals with significant scar formation, whereas wounds in fetal skin and oral mucosa heal with less scar formation. It has been postulated that oral fibroblasts share the similar properties with fetal fibroblasts. Therefore, oral mucosa wound may provide a novel model for studies establishing a treatment for minimizing scarring during adult tissue repair. Previously, we have isolated three overlapping cDNAs encoding 3.0 kb mRNA (wit 3.0) differentially expressed in oral mucosa wound. Western blot of transfected NIH3T3 fibroblasts showed that the translated fusion peptides of wit 3.0a and b, 40 KD and 43 KD respectively, were identified as single bands with or without a reducing treatment. Immunocytology and cell-fraction Western blot indicated that wit 3.0 peptides terminally localized in cytoplasmic region and appeared to associate with cytoskeletal structures. Collagen gel contraction assay showed that during the initial 24 hours, wit 3.0a and b transfection significantly accelerated the rate of collagen gel contraction (p<0.05) as compared with transfection and untreated controls. Conclusion: These data suggest that wit 3.0 may be involved in the fibroblast derived tissue contraction that primarily contributes to a rapid wound closure of the oral wound healing which may provide a novel clue to ameliorate the scar formation in adult wound healing.
