If those conditions that are throwing off the stats are expected to be minimally impactful/filtering few rows, then you can use the one tried-and-true optimizer hint (aside from materialized CTEs, stylized indexes, etc) --- OFFSET 0 at the end of a sub-query.
SELECT * FROM ( [your existing query without the sub-selects that are complicated and produce bad estimates] OFFSET 0 ) WHERE [your other conditions that don't produce good estimates] If there is correlation between field1 and field2, you might also look at CREATE STATISTICS assuming you are on PG 10 or 11. Before I do any of that, I would try LEFT JOIN for Table3 and Table4 then use the where conditon "AND 2 = COALESCE( Table3.Status, Table4.Status" and see if the optimizer likes that option better.