Yes, you can use OpenCL.
There is a bridge Pharo<—> OpenCL made by Ronie, available on smalltalkhub. 
Ronie has also been working on a DSL to easily write OpenCL applications. 

This is cool stuff! Have a look!

Alexandre
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Alexandre Bergel  http://www.bergel.eu
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> On Nov 18, 2014, at 6:12 PM, [email protected] wrote:
> 
> See
> https://news.ycombinator.com/item?id=8625280 
> <https://news.ycombinator.com/item?id=8625280>
> 
> [ (1 to: 100000000) sum ] timeToRun
> 
> Here we get out of the SmallInteger range...
> 
> Apart FFI'ing the thing, do we have other options?
> 
> Phil

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