Do You have Metabolic Syndrome?

[MinnieChat]

New Message on Pituitary Chat Do You have Metabolic Syndrome? Reply   Reply to Sender   Recommend Message 1 in Discussion From: MinnieChat http://www.hon.ch/News/HSN/510607.html   "TUESDAY, Dec. 3 (HealthScoutNews) -- Researchers have found that middle-aged men with a collection of conditions known as metabolic syndrome have an increased risk for both cardiovascular disease and death. Metabolic syndrome, which is also known as insulin resistance syndrome, is characterized by insulin resistance and elevated blood sugar levels, obesity marked by a pot belly, abnormal blood lipids, and high blood pressure. According to the study authors, metabolic syndrome is likely caused by some combination of obesity, a sedentary lifestyle, diet and genetic factors."  From the National Heart, Blood, and Lung Institute The Metabolic Syndrome The metabolic syndrome, which affects about one-quarter of all adults in the U.S., has emerged as just as strong a contributor to early heart disease as cigarette smoking. The metabolic syndrome, also known as syndrome X or insulin resistance syndrome, is a constellation of metabolic risk factors that significantly increases the risk for coronary events. The metabolic syndrome is identified by the presence of three or more of the following: abdominal obesity (waist circumference >40 inches in men or >35 inches in women); triglycerides 150 mg/dL; HDL cholesterol <40 mg/dL in men or <50 mg/dL in women; blood pressure 130/85 mmHg; and fasting glucose 110 mg/dL. First-line therapy for the metabolic syndrome is TLC, especially weight loss and physical activity, to address the underlying causes of overweight/obesity and physical inactivity. Additional information on the metabolic syndrome can be found in the "ATP III Executive Summary" and in the "ATP III Guidelines At-A-Glance Quick Desk Reference" on the NHLBI ATP III Web page (www.nhlbi.nih.gov/guidelines/cholesterol/). Am J Epidemiol 2002; 156:1070-1077. Copyright � 2002 by Johns Hopkins Bloomberg School of Public Health PRACTICE OF EPIDEMIOLOGY Metabolic Syndrome and Development of Diabetes Mellitus: Application and Validation of Recently Suggested Definitions of the Metabolic Syndrome in a Prospective Cohort Study </NOBR><NOBR>David E. Laaksonen1,2</NOBR>, <NOBR>Hanna-Maaria Lakka3,4</NOBR>, <NOBR>Leo K. Niskanen1</NOBR>, <NOBR>George A. Kaplan5</NOBR>, <NOBR>Jukka T. Salonen3,4,6</NOBR> and <NOBR>Timo A. Lakka3,7</NOBR> 1 Department of Medicine, Kuopio University Hospital, Kuopio, Finland. 2 Department of Physiology, University of Kuopio, Kuopio, Finland. 3 Research Institute of Public Health, University of Kuopio, Kuopio, Finland. 4 Department of Public Health and General Practice, University of Kuopio, Kuopio, Finland. 5 Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI. 6 Inner Savo Health Centre, Suonenjoki, Finland. 7 Kuopio Research Institute of Exercise Medicine, Kuopio, Finland. The World Health Organization (WHO) and the National Cholesterol Education Program (NCEP) recently proposed definitions for the metabolic syndrome. Little is known of their validity, however. The authors assessed the sensitivity and specificity of the definitions of the metabolic syndrome for prevalent and incident diabetes mellitus in a Finnish population-based cohort of middle-aged men (n = 1,005) followed for 4 years since the late 1980s. Four definitions based on the WHO and NCEP recommendations were compared. All definitions identified persons at high risk for developing diabetes during the 4-year follow-up (odds ratios = 5.0�8.8). The WHO definition including waist-hip ratio > 0.90 or body mass index 30 kg/m2 was the most sensitive (0.83 and 0.67) and least specific (0.78 and 0.80) in detecting the 47 prevalent and 51 incident cases of diabetes. The NCEP definition in which adiposity was defined as waist girth > 102 cm detected only 61% of prevalent and 41% of incident diabetes, although it was the most specific (0.89 and 0.90). The WHO definition seems valid as judged by its relatively high sensitivity and specificity in predicting diabetes. The NCEP definition including waist > 102 cm also identifies persons at high risk for diabetes, but it is relatively insensitive in predicting diabetes. Obesity and the Risk of Heart Failure - New England Journal of Medicine http://content.nejm.org/cgi/content/short/347/5/305 I just thought I'd mention this information since it has been in the new recently.  I know that this years Endocrine Society meeting will be focused on obesity and we will be reading alot about obesity and the discussion of Metabolic Syndrome will pepper the news. It is also possible, with pituitary patients, to be diagnosed concurrently with Metabolic Syndrome, and also for some patients (Cushing's), to be mis-diagnosed. I hope you find this to be interesting. Minnie View other groups in this category. Also on MSN: Start Chatting | Listen to Music | House & Home | Try Online Dating | Daily Horoscopes To stop getting this e-mail, or change how often it arrives, go to your E-mail Settings. Need help? If you've forgotten your password, please go to Passport Member Services. For other questions or feedback, go to our Contact Us page. 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