The prevalence of pituitary adenomas

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New Message on Pituitary Chat The prevalence of pituitary adenomas Reply   Reply to Sender   Recommend Message 1 in Discussion From: MinnieChat http://www3.interscience.wiley.com/cgi-bin/abstract/109085480/ABSTRACT   If you cannot access the full-text article - email me - Minnie   Original Article The prevalence of pituitary adenomas A systematic review Shereen Ezzat, M.D. 1 *, Sylvia L. Asa, M.D., Ph.D. 2, William T. Couldwell, M.D. 3, Charles E. Barr, M.D., M.P.H. 4, William E. Dodge, M.S., M.B.A. 4, Mary Lee Vance, M.D. 5, Ian E. McCutcheon, M.D. 6 1Department of Medicine, University of Toronto and Mount Sinai Hospital, Toronto, Ontario, Canada 2Department of Laboratory Medicine and Pathology, University of Toronto and Princess Margaret Hospital, Toronto, Ontario, Canada 3Department of Neurosurgery, University of Utah Medical School, Salt Lake City, Utah 4Pfizer, Inc., New York City, New York 5Department of Medicine, University of Virginia Medical School, Charlottesville, Virginia 6Department of Neurosurgery, The University of Texas M. D. Anderson Cancer Center, Houston, Texas email: Shereen Ezzat ([EMAIL PROTECTED]) *Correspondence to Shereen Ezzat, Department of Medicine, Mount Sinai Hospital, 600 University Avenue, Unit 437, Toronto, Ontario, M5G-1X5, Canada Fax: (416) 586-8834 Dr. Barr is currently an employee of Roche Laboratories, Inc. language=_javascript_>setDOI("ADOI=10.1002/cncr.20412")</SCRIPT> Funded by:  Pituitary Network Association, a nonprofit organization Keywords pituitary adenomas � immunochemistry � microadenomas � macroadenomas Abstract BACKGROUND Pituitary adenomas display an array of hormonal and proliferative activity. Once primarily classified according to size (microadenomas, < 1 cm; macroadenomas, 1 cm), these tumors are now further classified according to immunohistochemistry and functional status. With these additional classifications in mind, the goals of the current study were to determine the prevalence of pituitary adenomas and to explore the clinical relevance of the findings. METHODS The authors conducted a metaanalysis of all existing English-language articles in MEDLINE. They used the search string (pituitary adenoma or pituitary tumor) and prevalence and selected relevant autopsy and imaging evaluation studies for inclusion. RESULTS The authors found an overall estimated prevalence of pituitary adenomas of 16.7% (14.4% in autopsy studies and 22.5% in radiologic studies). CONCLUSIONS Given the high frequency of pituitary adenomas and their potential for causing clinical pathologies, the findings of the current study suggest that early diagnosis and treatment of pituitary adenomas should have far-reaching benefits. Cancer 2004. � 2004 American Cancer Society. View other groups in this category. Also on MSN: Start Chatting | Listen to Music | House & Home | Try Online Dating | Daily Horoscopes To stop getting this e-mail, or change how often it arrives, go to your E-mail Settings. Need help? If you've forgotten your password, please go to Passport Member Services. For other questions or feedback, go to our Contact Us page. If you do not want to receive future e-mail from this MSN group, or if you received this message by mistake, please click the "Remove" link below. On the pre-addressed e-mail message that opens, simply click "Send". Your e-mail address will be deleted from this group's mailing list. Remove my e-mail address from Pituitary Chat.