----------------------------------------------------------- New Message on Pituitary Chat
----------------------------------------------------------- From: MinnieChat Message 2 in Discussion There are some clinical cases where the IGF-1 was normal in all tests (levels adjusted for age); however, since the data is pretty slim, the recommendation would be to really consider traveling and see an acromegaly specialist. Dr. Pam Freda, Department of Medicine, Columbia University College of Physicians & Surgeons, 630 West 168th Street, New York, NY 10032, USA. [EMAIL PROTECTED], has seen and written about difficult diagnostic cases. I do know that your husband will need an oral glucose tolerance test, and, if clinical suspecion is strong, a gh circadian blood sampling (done over 24 hours). Good luck! Here are some abstracts from Pubmed Lim DJ, Kwon HS, Cho JH, Kim SH, Choi YH, Yoon KH, Cha BY, Lee KW, Son HY, Kang SK. Acromegaly associated with type 2 diabetes showing normal IGF-1 levels under poorly controlled glycemia. Endocr J. 2007 Aug;54(4):537-41. Epub 2007 Jun 13. PMID: 17575366 [PubMed - indexed for MEDLINE] Freda PU. Current concepts in the biochemical assessment of the patient with acromegaly. Growth Horm IGF Res. 2003 Aug;13(4):171-84. Review. PMID: 12914750 [PubMed - indexed for MEDLINE] Brooke AM, Drake WM. Serum IGF-I levels in the diagnosis and monitoring of acromegaly. Pituitary. 2007 Jun;10(2):173-179. PMID: 17431794 [PubMed - as supplied by publisher] Tzanela M. Dynamic tests and basal values for defining active acromegaly. Neuroendocrinology. 2006;83(3-4):200-4. Epub 2006 Oct 13. Review. PMID: 17047383 [PubMed - indexed for MEDLINE] Popovic V. Are there alternative tests for diagnosis of acromegaly? J Endocrinol Invest. 2005;28(11 Suppl International):73-4. Review. PMID: 16625850 [PubMed - indexed for MEDLINE] ----------------------------------------------------------- To stop getting this e-mail, or change how often it arrives, go to your E-mail Settings. http://groups.msn.com/PituitaryChat/_emailsettings.msnw Need help? If you've forgotten your password, please go to Passport Member Services. http://groups.msn.com/_passportredir.msnw?ppmprop=help For other questions or feedback, go to our Contact Us page. http://groups.msn.com/contact If you do not want to receive future e-mail from this MSN group, or if you received this message by mistake, please click the "Remove" link below. On the pre-addressed e-mail message that opens, simply click "Send". Your e-mail address will be deleted from this group's mailing list. mailto:[EMAIL PROTECTED]
