> On 20 Aug 2015, at 10:59, Vadim Axel <[email protected]> wrote:
> 
> Very simple question: to what extent representation similarity can be 
> interpreted as similarity of cognitive processing? 
> 
> Consider a toy sample, where I have two experiments. In Exp.1 there is task A 
> and baseline1. In Exp.2 there there is task B  and baseline2. For each 
> experiment, I generate t-contrasts:  A > baseline1 and  B > baseline2. To 
> check for similarity between tasks A and B, I can run conjunction analysis 
> (spatial overlap). For stronger evidence, I can for each experiment, extract 
> t-values for some predefined ROIs. Then, I run Pearson correlation across 
> voxels within a ROI. Using across subjects statistics I can show that in some 
> ROIs the correlation between experiments is above 0. Can this result be 
> interpreted, as having similarity of cognitive processing during two tasks?

It would indicate that *something* is similar (at a pattern level) between the 
two tasks. You may possibly interpret this as cognitive processing, but 
cognitive processing is a rather broad concept. Pattern similarity can arise 
through a variety of different mechanisms, including trivial ones.

> Also, does someone know about papers that examined similarity between 
> experiments using a contrast (and not Haxby_2001_like_style of patterns of 
> single faces vs cats). In my case, Exps 1 and 2 have very different designs, 
> so A and B cannot be compared directly. In general, good references for 
> citing are highly appreciated.

This may be considered as shameless self-promotion, but I have done some work 
on executing versus observing different manual actions [1], and imagery and 
execution/observation of such actions [2]. 

[1] Oosterhof, N. N., Wiggett, A. J., Diedrichsen, J., tipper, S. P. & Downing, 
P. E. Surface-based information mapping reveals crossmodal vision-action 
representations in human parietal and occipitotemporal cortex. J. Neurophysiol. 
104, 1077–1089 (2010).
[2] Oosterhof, N. N., Tipper, S. P. & Downing, P. E. Visuo-motor imagery of 
specific manual actions: A multi-variate pattern analysis fMRI study. 
Neuroimage 63, 262–271 (2012).


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