Same problem here, but I only had a few channels at the time.
I lost all of my channels after a BSOD in Windows 2000 while Plucker was syncing..
It was as good a time as any to clean things up & install the latest version... :)
Andrew
>
> The instruction at "0x005f4e97" referenced memory at "0x00bf4da3". The
> memory could not be written.
>
> unknown software exception (0xc0000027) occurred in the application at
> location 0x77e86e8b

