Heather, take a look at http://www.pytables.org/moin.  I've not ever used it, 
so I can not speak to its quality or speed.

When I was at JPL in the early '90s and NASA was planning for the Earth 
Observation System, they were trying to figure out how to deal with petabytes 
of data a day.   Not an easy problem two decades ago.

Rick


On Oct 20, 2011, at 3:49 PM, Kevin Turner wrote:

> On Thursday, October 20, 2011 3:29 PM, "Ryan Roser"
> <[email protected]> wrote:
>> a medium amount of data, 100's-1000's of GBs
> 
> I like how you describe a few terabytes as "a medium amount of data."
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