http://english.aljazeera.net/NR/exeres/43904F69-331D-4AE0-8280-98DD373D3B44.htm
Curry ingredient fights skin cancer
Tuesday 12 July 2005, 2:32 Makka Time, 23:32 GMT
The compound that makes curry yellow could help fight skin cancer, US
researchers say.
They said curcumin, found in the spice turmeric, interferes with melanoma
cells.
Tests in laboratory dishes show that curcumin made melanoma skin cancer cells
more likely to self-destruct in a process known as apoptosis.
The same team has found that curcumin helped stop the spread of breast cancer
tumour cells to the lungs of mice.
Bharat Aggarwal and colleagues of the Department of Experimental Therapeutics
at the University of Texas MD Anderson Cancer Centre in Houston treated three
batches of melanoma cells, known as cell lines, with curcumin at different
doses and for varying times.
Potent suppressor
The curcumin suppressed two proteins that tumour cells use to keep themselves
immortal, the researchers write in next month's issue of the journal Cancer.
"Based on our studies, we conclude the curcumin is a potent suppressor of cell
viability and inducer of apoptosis in melanoma cell lines," Aggarwal's team
wrote.
"Future investigation to determine the effects of curcumin in animal models of
melanoma and clinical trials are planned."
Earlier research has shown that curcumin, which acts as an antioxidant, can
help prevent tumours from forming in the laboratory.
Aggarwal said people who eat plenty of turmeric have lower rates of some
cancers, although the spice itself has not been shown to reduce cancer risk in
people.
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