http://www.smh.com.au/lifestyle/wellbeing/fish-oil-reduces-youth-psychosis-20100201-n8v4.html


Fish oil 'reduces youth psychosis' 
NICK MILLER 
February 2, 2010 
FISH oil supplements can dramatically reduce the chance of young people 
developing psychosis or schizophrenia, Australian researchers say.

Lead researcher Paul Amminger said colleagues had laughed when he proposed the 
study, but the results surprised even him.

The adolescent psychiatrist from the University of Melbourne's Orygen research 
centre says doctors should now consider fish oil as a genuine alternative to 
expensive and more risky anti-psychotics when a young patient is showing early 
signs of mental illness. And he believes the oil's omega-3 fatty acids might 
help prevent depression and drug abuse.

In the study, published in the Archives of General Psychiatry journal, 41 
high-risk patients were given four fish oil capsules a day for three months. 
Only two of them developed a psychotic disorder, compared with 11 of another 40 
who took a placebo.

Orygen, home of the Australian of the Year Pat McGorry who was a co-author on 
this study, has played a world-leading role in promoting the power of early 
intervention on youth psychosis.

However this has sparked some controversy, associate professor Amminger said.

''People argued that [pharmaceutical] medication might have too many 
side-effects at the early stage of developing a disorder,'' he said.

High-powered anti-psychotic drugs can come with metabolic changes, sexual 
dysfunction and weight gain which are often not acceptable for young people, 
leading to high drop-out rates.

Very few people dropped out of the fish oil treatment regime, and a 12-month 
follow up showed the effect seemed to protect the brain even after the patient 
stopped taking the pills.

''I hope the whole scientific community takes on this idea and takes this area 
more seriously,'' associate professor Amminger said. ''Originally some of my 
colleagues were laughing at us for saying we might prevent schizophrenia with 
something like fish oil.''

The researchers are now planning two new studies based on the results.

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