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Resveratrol Cited as Key to Slowing the Aging Process in Barbara Walters Special

Resveratrol is key to living to be 150 years old. Scientists have found that 
resveratrol works on a gene called SERT1 that controls the aging process. 

Pittsboro, NC, April 08, 2008 --(PR.com)-- Barbara Walters presented cutting 
edge research on a TV special on ABC called ?Live to be 150? Can You Do It?? 
Several new technologies are getting people closer to the quest to live longer 
and healthier lives.

Dr. David Sinclair, a founder of Sirtris Pharmaceuticals and a professor at 
Harvard Medical School, talked about a specific gene that is activated by 
resveratrol that slows the aging process. Resveratrol is an antioxidant found 
in several fruits. Muscadine grapes, which grow in the Southeastern US, were 
found to have especially high concentrations of natural resveratrol.

Dr. Sinclair stated, ?Resveratrol works on a gene called SERT1, and this is the 
gene that controls the aging process.? With the gene activated by a high dose 
of resveratrol, the mice ran twice as far as the untreated mice. He noted, 
?They didn?t get heart disease, cancer, even osteoporosis and they lived thirty 
percent longer.?





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Resveratrol is a phytoalexin produced naturally by several plants when under 
attack by bacteria or fungi. Phytoalexins are antibacterial and anti-fungal 
chemicals produced by plants as a defense against infection by pathogens. 
Resveratrol has also been produced by chemical synthesis,[1] and is sold as a 
nutritional supplement derived primarily from Japanese knotweed. A number of 
beneficial health effects, such as anti-cancer, antiviral, neuroprotective, 
anti-aging, and anti-inflammatory effects have been reported. Resveratrol is 
found in the skin of red grapes and is a constituent of red wine but, based on 
extrapolation from animal trials, apparently not in sufficient amounts to 
explain the "French paradox" that the incidence of coronary heart disease is 
relatively low in southern France despite high dietary intake of saturated fats.

  
Resveratrol Wine Antioxidant for anti aging and weight loss 200mg 80 capsules 

Supplement Facts
Serving Size:
1 Capsule
Servings Per Container:
80

Amount per Serving
% Daily Value


Vitamin C as Ascorbic Acid
 60 mg
100%


Red Wine Complex 
 200 mg*

Red Wine Extract (Vitis vinifera) (grape skin), Vitamin C (as ascorbic acid), 
Citrus Bioflavanoids (citrus sinensis) (fruit), Grapeseed Extract (Vitis 
vinifera) (seed) (Standardized to contacin Polyphenois), Procyanidol TM (Grape 
Extract (Vitis rotundifolia) (skin and seed) (Contains Ellagic Acid and 
Resveratrol)


* Daily Value not established.
Suggested Use:  For adults, take one (1) capsule one to two times daily, 
preferably with a mean.  As a reminder, discuss the supplements and medications 
you take with your health care providers.


 
 
---------

Red wine has long been touted as heart healthy. Some have suggested that the 
apparent health benefits of red wine, namely reducing your risk of heart 
disease, are behind the so-called French paradox. The French are regular 
drinkers of red wine and have relatively high amounts of saturated fat in their 
diet. Despite this fat intake, the French have lower rates of heart disease.

While the news about red wine might sound great if you enjoy a glass of red 
wine with your evening meal, doctors are wary of encouraging anyone to drink 
alcohol because too much alcohol can have a host of harmful effects on your 
body.

But despite the caution, doctors do agree that something in red wine appears to 
help your heart, though it's unclear just exactly what that "something" is. 
Recent research has indicated a substance called resveratrol, which is found in 
the skin and seeds of grapes used to make wine, has promising heart-healthy 
benefits.
The benefits of resveratrol, found primarily in red wine, are still being 
investigated, even though thousands of laboratory studies have been completed.

----------

Resveratrol pills are now available as a health supplement and the compound is 
included in a few of the better daily multi nutrient formulas. As with most 
natural supplements, opinions about resveratrol vary, but so far, no negative 
side effects have been found.

First identified in 1963 as the effective ingredient in the Asian Folk medicine 
called ko-jo-kon in Japanese or polygonum capsidatum in Latin, resveratrol was 
later found in grapevines and finally, in 1992, in red wine.

It is because of the believed benefits of resveratrol that many practitioners 
suggest drinking red wine (just a 4 oz. glass) with dinner. Resveratrol pills 
or supplements containing the compound are an option for non drinkers.

Although opinions about resveratrol benefits to human health vary, scientists 
know that the compound has antibiotic capabilities, protects plants from 
disease, fungus and viral infections. Like many plant compounds, it is an 
antioxidant, meaning that it protects the plants from the damaging affects of 
oxidative stress.

The reason that opinions about resveratrol and other antioxidants vary is that 
research results differ. Many researchers are not sure if plant antioxidants 
provide the same protection to humans that they do to the plants.

This opinion is becoming increasingly less popular, as research studies 
conclude again and again that those people who follow a diet rich in a variety 
of multi colored fruits and vegetables have less heart disease, cancer and 
other chronic diseases.

Antioxidants are the compounds that give fruits and vegetables their vibrant 
colors, each performing a specific purpose in the life of the plant.

There are many antioxidants found in nature; resveratrol is but one. In order 
to ensure long term good health and receive the most protection from life 
threatening and chronic diseases, numerous antioxidants should be included in 
your daily supplement routine. In other words, resveratrol pills by themselves 
are not enough.

Many positive opinions about resveratrol have been reported in major 
publications. There have been positive reports in the Oxford Journal and the 
Federation of American Societies for Experimental Biology. These reports 
indicate that the benefits of resveratrol to modern medicine and human health 
are multi-faceted.

Besides being an antioxidant, resveratrol is an anti-mutagen and a strong 
anti-inflammatory. An anti-mutagen is a compound that inhibits the mutation of 
healthy normal cells into cancerous growths and tumors. You are probably 
familiar with the term anti-inflammatory. Many common over the counter pain 
relievers are anti-inflammatory medications, but there are many natural 
anti-inflammatories.

Chronic inflammation is believed to be at the root of many diseases, including 
heart disease and cancer. Synthetic anti-inflammatories cannot be taken on a 
regular basis to prevent chronic inflammation without risking other health 
problems. Natural anti-inflammatories, on the other hand, are found primarily 
in plant foods and can be consumed on a regular basis throughout a person?s 
life with no side effects.

Since it is one of the natural anti-inflammatories, it is believed that the 
benefits of resveratrol include the prevention of heart disease, cancer and 
other diseases associated with chronic inflammation. These are the benefits 
that resveratrol pills may also provide.

Other benefits of resveratrol are being studied. It may have an anti-aging 
effect on cells and is being studied for its effects on Alzheimer?s. Benefits 
of resveratrol in cancer prevention, suppression and treatment are being 
studied.

A recent report in the Journal of Infectious Diseases states that resveratrol 
decreased the reproduction of the influenza virus in cell lines and rats, in 
other words it may be useful in preventing or treating the flu.

Although opinions about resveratrol may vary, there is no evidence that large 
amounts of resveratrol are harmful in any way. Large doses showed no adverse 
effects in rats tested.

In conclusion, the benefits of resveratrol to all systems of the human body 
have been or are currently being studied. Resveratrol pills may not be a 
miracle drug, but since most people take a daily multi-vitamin, choosing one of 
the better supplements that contains this compound is most likely a wise health 
decision.

*These statements have not been evaluated by the Good and drug administration.  
This peoduct is not intended to diagnose, treat, cure or prevent any disease.

6 Reasons Why You Should Be Taking Resveratrol Supplements 

1.   Resveratrol may increase your lifespan 

Researchers believe that Resveratrol tricks the body into believing that it is 
under the effects of a calorie deficient diet and thus receives the beneficial 
health effects such as an increased lifespan as a result.

2.   Resveratrol may help you lose weight 

Resveratrol acts as an estrogen blocker. Estrogen has some negative effects on 
the body including decreased muscle mass and increased fat storage; studies 
have demonstrated that Resveratrol actually increased the hormones responsible 
for signaling the body to produce more testosterone 2.7 times greater than the 
placebo. Increased free testosterone will actually lead to increased muscle 
mass and decreased body fat. Second, Resveratrol helps to regulate insulin 
production in the pancreas. High levels of insulin secretion leads to increased 
fat storage, which may eventually lead to insulin resistance and therefore Type 
II Diabetes. 

3.   Resveratrol may aid in cancer prevention 

Resveratrol is known to inhibit all 3 major stages of tumors development, 
initiation, promotion and progression, and the list of tumors it may inhibit is 
astounding, including prostate cancer, breast cancer, melanoma, liver cancer, 
brain cancer, pancreatic cancer, kidney cancer, colon cancer, ovarian and 
cervical cancer, lymphoma and it even appears to act as an anti-leukemia agent.

4.  Resveratrol may provide anti-fungal, antiviral and antibiotic benefits 

Resveratrol is anti-fungal in nature and has shown to inhibit the growth of 
both mold and fungus. Research has also shown that Resveratrol also has 
anti-viral properties. Studies have revealed that Resveratrol inhibits the 
growth of viruses such as herpes, influenza, and has also shown to improve the 
potency of certain antiretroviral drugs used against HIV.

5.   Resveratrol may act as a neuroprotective agent 

New research on Resveratrol has shed light on some of its neuroprotective 
attributes. After serious brain injuries, Resveratrol treatment may vastly 
improve the ability of the brain to recover, especially from secondary brain 
injury. Further, it is believed that due to its activation of the SIRT1 
longevity gene, Resveratrol may promote neuronal survival in the brain and it 
may provide a practical application to help treat neuro-degenerative disorders 
such as Parkinsons and Alzheimers disease.

6.  Resveratrol may provide cholesterol-lowering cardio-vascular benefits 

Researchers believe that Resveratrol is partially responsible for the 
cholesterol-lowering effects of red wine. Epidemiologic and clinical studies 
suggest that high consumption of Resveratrol-rich foods may result in reduced 
cardiovascular disease risk, lowered total cholesterol, and lowered LDL 
cholesterol. Resveratrol's antioxidant properties may again be the mechanism at 
work in reducing the oxidation of LDL cholesterol.



Resveratrol ? Daily Dosage Guidelines 

There are a confusing number of resveratrol supplements on the market today. In 
order to make an informed decision, it?s important to understand the compound 
itself. With so much attention being focused on this product, it?s obvious that 
there is going to be a lot of confusion as well.

Resveratrol, marketed as a nutritional supplement, is typically an extract of 
Polygonum cuspidatum. Both the cis- form and the trans- form are present in 
Polygonum cuspidatum. The trans-resveratrol isomer is the isomer which provides 
the health benefits. Nutritional supplements contain extracts that can be 
standardized to deliver any percentage of resveratrol. In its various forms, 
the extract percentage is typically: 98%, 50%, 25%, 16%, or 8% resveratrol.

So it is important to check the product label to determine the amount of 
trans-resveratrol present in each serving. If the product label states the 
supplement contains 200 mg of resveratrol ?standardized to 25%?, then each 
serving contains only 50 mg of trans-resveratrol (200 mg * 0.25 = 50 mg).

Currently there is no generally recommended daily dose of trans-resveratrol for 
people to use as a guideline. The dosage amount needed to replicate some of the 
documented studies would be approximately 22 mg per one kg of body weight. For 
a 160 pound person, that would equal nearly 1600 mg of trans-resveratrol per 
day.  However, some studies indicate that for beneficial effects of 
resveratrol, a person should take at least 500 mg of trans-resveratrol per day.

Resveratrol has a short active duration in the human body. Some studies 
indicate that resveratrol is metabolized by the body after approximately 90 
minutes. So when taking resveratrol for its health benefits, it may be helpful 
to take it 2-3 times per day instead of just once a day.


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