http://www.granma.cu/ingles/2005/marzo/vier4/11tetra.html

 
CUBAN IMMUNIZATION PROGRAM

Uses vaccine against diphtheria, whooping cough, tetanus and hepatitis B 

. All children born from January 1, 2005 onwards will be immunized with the 
DPT-HB tetravalent, except for those children whose mothers carry the hepatitis 
B virus; they will receive similar protection, but under a different 
vaccination plan

BY LILLIAM RIERA-Granma International staff writer-

. BEGINNING March 1, 2005, Cuba's Immunization Program is now using a 
Cuban-produced vaccine that protects children from four diseases ( diphtheria, 
whooping cough, tetanus and hepatitis B) .

Prof. Miguel Galindo, head of the Ministry of Public Health's Immunization 
Program, told Granma daily that all children born from January 1, 2005 onwards 
would be immunized with the tetravalent vaccine DPT-HB, except for those 
children whose mothers carry the hepatitis B virus; these will receive similar 
protection, but under a different vaccination plan.

Babies whose mothers are healthy will receive the first dose when they are two 
months old, subsequent doses when they are four and six months old, and at 18 
months, they will receive a booster with the triple DPT (diphtheria, whooping 
cough and tetanus).

Children whose mothers carry hepatitis will receive a second dose of the Cuban 
recombination vaccine against hepatitis B ( Heberbiovac HB) at the age of one 
month (these babies received their first dose when they were born, as all Cuban 
children do). They receive the third dose at two months and a booster after 
turning one year. These children will be immunized with the triple DPT at two, 
four and six months, and receive a booster at 18 months.

These are high quality and effective vaccines, and provide 95% protection 
against diphtheria and tetanus, 80% against whooping cough and 98% against 
hepatitis B.

The Cuban vaccination program protects children from 13 illnesses. Its efficacy 
has eliminated nine of them at the national level, including poliomyelitis - 
since 1962 - and neonatal tetanus since 1972.

The Finlay Institute supplies the Center for Genetic and Biotechnological 
Engineering ( CIGB) with the first three components ( diphtheria and tetanus 
anatoxines, and pertussis compound, the microorganism that causes whooping 
cough) needed to produce the tetravalent vaccine, according to Ricardo Montero, 
president of Finlay Vaccines S.A. in February 2004, who spoke with Granma 
International.

This company is 100% Cuban, and exclusively represents the products, projects 
and services of the Finlay Institute, part of the scientific complex in western 
Havana.

In the interview, Montero explained that this Institute participates in the 
Cuban program of combined vaccines, "in close collaboration with the CIGB," the 
institution leading the project.

Combined vaccines protect children from several illnesses with a single 
injection, avoiding the risk of increased side effects that occurs when these 
vaccines are administered separately, such as fever, general discomfort and 
reddened skin in the area of the shot, common in 30% of those immunized.

At the end of last year, a Finlay Institute plant intiated operations to 
produce the three first components of a tetravalent vaccine. According to 
Montero, this will "guarantee sufficient supplies, together with those created 
by the CIGB and the National Center of Bio-prepared Products, to be able to 
offer vaccines to the World Health Organization and any country that may 
request them."

Likewise, it was reported that investments in technological equipment at the 
CIGB has made it possible to double the production of Heberbiovac HB, thus 
giving the center the potential to produce nearly six million doses for 
children this year. Such a figure would create a real opportunity to make this 
vaccine available to other regions in the world.

However, Cuban researchers aren't stopping there. They continue to work on 
producing a pentavalent vaccine ( DPT-HB-Hlb) against diphtheria, whooping 
cough, tetanus, hepatitis B and Haemophilus influenzae Type b. The latter is 
responsible for a large percentage of cases of meningitis, pneumonia and 
otitis, resulting in the deaths of half a million children worldwide.

Quimi- Hib is the commercial name of the Cuban vaccine against that bacterium. 
In June 2003, Dr. Vicente V�rez Bencomo, its principal creator, explained to GI 
that this is "the first vaccine in the world artificially created in a 
laboratory," and that the new shot, "when used by the national Immunization 
Program, will enable the country to save two to three million dollars per year 
in imports."

Since August 2004, a plant to produce the active pharmaceutical components of 
this vaccine has been operating at the CIGB. With an installed capacity of 10 
million units annually, this plant meets 100% of the country's needs, and it 
could increase production fivefold to be able to export significant amounts in 
the near future. 


[Non-text portions of this message have been removed]



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