http://www.guardian.co.uk/science/2008/jun/16/neuroscience.psychology


Gay men and heterosexual women have similarly shaped brains, research shows

· Lesbians and heterosexual men show same pattern


Striking similarities between the brains of gay men and straight women have 
been discovered by neuroscientists, offering fresh evidence that sexual 
orientation is hardwired into our neural circuitry.

Scans reveal homosexual men and heterosexual women have symmetrical brains, 
with the right and left hemispheres almost exactly the same size. Conversely, 
lesbians and straight men have asymmetrical brains, with the right hemisphere 
significantly larger than the left.

Scientists at the prestigious Stockholm Brain Institute in Sweden also found 
certain brain circuits linked to emotional responses were the same in gay men 
and straight women.

The findings, published tomorrow in the US journal Proceedings of the National 
Academy of Sciences, suggest the biological factors that influence sexual 
orientation - such as exposure to testosterone in the womb - may also shape the 
brain's anatomy.

The study, led by the neurobiologist Ivanka Savic, builds on previous research 
that has identified differences in spatial and verbal abilities related to sex 
and sexual orientation. Tests have found gay men and straight women fare better 
at certain language tasks, while heterosexual men and lesbians tend to have 
better spatial awareness.

Savic and her colleague Per Linström took MRI brain scans of 90 volunteers who 
were divided into four groups of similar ages according to whether they were 
male, female, heterosexual or homosexual. The scans showed the right side of 
the brain in heterosexual men was typically 2% larger than the left. Lesbians 
showed a similar asymmetry, with the right hand side of the brain 1% larger 
than the left.

Scans on homosexual men and heterosexual women revealed both sides of the brain 
were the same size.

The results could explain a University of London study earlier this year that 
found gay men and straight women share a poor sense of direction compared with 
heterosexual men, and were more likely to navigate using landmarks alone.

The right hand side of the brain dominates spatial capabilities, so may be 
slightly more developed in heterosexual men and lesbians. An earlier study by 
the same team found gay men and straight women outperformed lesbians and 
straight men at tasks designed to test verbal fluency.

Savic's team has yet to confirm whether the differences in brain shape are 
responsible for sexual orientation, or are a consequence of it. To find out, 
they have begun another study to investigate brain symmetry in newborn babies, 
to see if it can be used to predict their future sexual orientation.

"These differences might be laid down during brain development in the womb, or 
they could happen after birth, though it could very likely be a combination of 
the two," said Savic.

In another series of tests, Savic and Lindström used a technique called 
positron emission tomography (PET) to look at brain wiring in a smaller group 
of volunteers. They found heterosexual women and gay men shared brain circuitry 
linking a region called the amygdala, which plays a key role in emotional 
responses, to other parts of the brain.

The research is part of a larger effort to identify differences between the 
male and female brain, in the hope they will shed light on why some mental 
disorders affect men and women differently. For example, major depressive 
disorders are far more common and persistent in women, while autism is around 
four times more common in boys than girls.

"There's a well known uneven sex distribution in the number of psychiatric 
disorders and trying to understand sex differences, and differences in 
orientation, may give you a hint of the mechanism underlying these diseases," 
said Savic.


© 2013 Guardian News and Media Limited or its affiliated companies. All rights 
reserved.





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