AJaran Islam mengatakan "sebaik2 manusia adalah yang hidupnya 
bermanfaat/berguna buat orang lain" dan "alam semesta".  "Seburuk2 manusia 
adalah yg berumur panjang tetapi membuat kerusakan dimuka bumi (dalam berbagi 
skalanya)"

--- Pada Jum, 16/7/10, utusan.allah <[email protected]> menulis:

Dari: utusan.allah <[email protected]>
Judul: [proletar] SD:Calorie Restriction: Scientists Take Important StepToward 
'Fountain of Youth'
Kepada: [email protected]
Tanggal: Jumat, 16 Juli, 2010, 5:14 PM







 



  


    
      
      
      

Bagi yang mau hidup lama..



--



        Web address:

     http://www.sciencedaily.com/releases/2009/12/

     091222105219.htm   

Calorie Restriction: Scientists Take Important Step Toward 'Fountain of Youth'

enlarge



Glucose molecular model. (Credit: iStockphoto/Martin McCarthy)



ScienceDaily (Dec. 26, 2009) — Going back for a second dessert after your 
holiday meal might not be the best strategy for living a long, cancer-free life 
say researchers from the University of Alabama at Birmingham. That's because 
they've shown exactly how restricted calorie diets -- specifically in the form 
of restricted glucose -- help human cells live longer.



This discovery, published online in The FASEB Journal, could help lead to drugs 
and treatments that slow human aging and prevent cancer.



"Our hope is that the discovery that reduced calories extends the lifespan of 
normal human cells will lead to further discoveries of the causes for these 
effects in different cell types and facilitate the development of novel 
approaches to extend the lifespan of humans," said Trygve Tollefsbol, Ph.D., a 
researcher involved in the work from the Center for Aging and Comprehensive 
Cancer Center at the University of Alabama at Birmingham. "We would also hope 
for these studies to lead to improved prevention of cancer as well as many 
other age-related diseases through controlling calorie intake of specific cell 
types."



To make this discovery, Tollefsbol and colleagues used normal human lung cells 
and precancerous human lung cells that were at the beginning stages of cancer 
formation. Both sets of cells were grown in the laboratory and received either 
normal or reduced levels of glucose (sugar). As the cells grew over a period of 
a few weeks, the researchers monitored their ability to divide, and kept track 
of how many cells survived over this period.



They found that the normal cells lived longer, and many of the precancerous 
cells died, when given less glucose. Gene activity was also measured under 
these same conditions. The reduced glucose caused normal cells to have a higher 
activity of the gene that dictates the level of telomerase, an enzyme that 
extends their lifespan and lower activity of a gene (p16) that slows their 
growth. Epigenetic effects (effects not due to gene mutations) were found to be 
a major cause in changing the activity of these genes as they reacted to 
decreased glucose levels.



"Western science is on the cusp of developing a pharmaceutical fountain of 
youth" said Gerald Weissmann, M.D., Editor-in-Chief of The FASEB Journal. "This 
study confirms that we are on the path to persuading human cells to let us to 
live longer, and perhaps cancer-free, lives."

Email or share this story:

| More



Story Source:



The above story is reprinted (with editorial adaptations by ScienceDaily staff) 
from materials provided by Federation of American Societies for Experimental 
Biology, via EurekAlert!, a service of AAAS.



Journal Reference:



1. Li et al. Glucose restriction can extend normal cell lifespan and impair 
precancerous cell growth through epigenetic control of hTERT and p16 
expression. The FASEB Journal, 2009; DOI: 10.1096/fj.09-149328



Need to cite this story in your essay, paper, or report? Use one of the 
following formats:

APA



MLA

Federation of American Societies for Experimental Biology (2009, December 26). 
Calorie restriction: Scientists take important step toward 'fountain of youth'. 
ScienceDaily. Retrieved July 16, 2010, from http://www.sciencedaily.com­ 
/releases/2009/12/091222105219.htm



Note: If no author is given, the source is cited instead.





    
     

    
    


 



  







[Non-text portions of this message have been removed]



------------------------------------

Post message: [email protected]
Subscribe   :  [email protected]
Unsubscribe :  [email protected]
List owner  :  [email protected]
Homepage    :  http://proletar.8m.com/Yahoo! Groups Links

<*> To visit your group on the web, go to:
    http://groups.yahoo.com/group/proletar/

<*> Your email settings:
    Individual Email | Traditional

<*> To change settings online go to:
    http://groups.yahoo.com/group/proletar/join
    (Yahoo! ID required)

<*> To change settings via email:
    [email protected] 
    [email protected]

<*> To unsubscribe from this group, send an email to:
    [email protected]

<*> Your use of Yahoo! Groups is subject to:
    http://docs.yahoo.com/info/terms/

Kirim email ke