makanan haram, haram, haram!, Mati tidak  bisa masuk sorga, cilaka busaar tak 
bisa ketemu miss angel.


  ----- Original Message ----- 
  From: Jusfiq 
  To: [email protected] 
  Sent: Wednesday, October 06, 2010 12:01 PM
  Subject: [proletar] Black rice anthocyanins inhibit cancer cells invasion via 
repressions of MMPs an


    

  Makan tape beras hitam yuk..

  Tapi runyamnya buat orang Islam tape itu mengandung alkohol...

  --

  Chem Biol Interact. 2006 Nov 7;163(3):218-29. Epub 2006 Aug 17.
  Black rice anthocyanins inhibit cancer cells invasion via repressions of MMPs 
and u-PA expression.

  Chen PN, Kuo WH, Chiang CL, Chiou HL, Hsieh YS, Chu SC.

  Institute of Biochemistry and Biotechnology, Chung Shan Medical University, 
No. 110, Section 1, Chien Kuo N. Road, Taichung 402, Taiwan.
  Abstract

  Tumor metastasis is the most important cause of cancer death and various 
treatment strategies have targeted on preventing the occurrence of metastasis. 
Anthocyanins are natural colorants belonging to the flavonoid family, and are 
wildly used for their antioxidant properties. Here, we provided molecular 
evidence associated with the anti-metastatic effects of peonidin 3-glucoside 
and cyanidin 3-glucoside, major anthocyanins extracted from black rice (Oryza 
sativa L. indica), by showing a marked inhibition on the invasion and motility 
of SKHep-1 cells. This effect was associated with a reduced expression of 
matrix metalloproteinase (MMP)-9 and urokinase-type plasminogen activator 
(u-PA). Peonidin 3-glucoside and cyanidin 3-glucoside also exerted an 
inhibitory effect on the DNA binding activity and the nuclear translocation of 
AP-1. Furthermore, these compounds also exerted an inhibitory effect of cell 
invasion on various cancer cells (SCC-4, Huh-7, and HeLa). Finally, 
anthocyanins from O. sativa L. indica (OAs) were evidenced by its inhibition on 
the growth of SKHep-1 cells in vivo.

  PMID: 16970933 [PubMed - indexed for MEDLINE]



  

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