Hello Michael --

Have you found the solution to your issue? I am having the exact same issue 
and cannot figure out how to correct.

My info for the versions I am using is below:
408 INFO: PyInstaller: 3.6
409 INFO: Python: 3.8.2
409 INFO: Platform: Windows-10-10.0.18362-SP0

I get the same info:

line 37, in pywin32error
    raise error(exception.winerror, exception.function, exception.strerror)
win32ctypes.pywin32.pywintypes.error: (1920, 'LoadLibraryEx', 'The file 
cannot be accessed by the system')


Any help would be appreciated. Thanks!

Jamison

On Tuesday, November 19, 2019 at 4:39:26 AM UTC-5, Michael wrote:
>
> Hi there. I am having trouble with this file:
>
>
> "C:\Users\Michael\AppData\Local\Packages\PythonSoftwareFoundation.Python.3.7_qbz5n2kfra8p0\LocalCache\local-packages\Python37\site-packages\win32ctypes\pywin32\pywintypes.py"
>
>
> Powershell says:
>
>
> line 37, in pywin32error
>     raise error(exception.winerror, exception.function, exception.strerror)
> win32ctypes.pywin32.pywintypes.error: (1920, 'LoadLibraryExW', 'The file 
> cannot be accessed by the system.')
>
>
> I have tried running powershell as admin and also adding the entire 
> directory to PATH but it still refuses to work. Any help greatly 
> appreciated. 
>
> Regards, Michael
>

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