The ROI (and all sub classes) have a hard coded handleSize attribute set to 
5 (pixels?). See here 
<https://github.com/pyqtgraph/pyqtgraph/blob/3de5d580ac2dfa6ea83aa178292f172b78d4b1df/pyqtgraph/graphicsItems/ROI.py#L183>
.

This is very small for large monitors and large images. I have not found a 
way to change this without class inheritance and overwriting the 
addHandle() function.

Is there a way to simply set the handleSize and then redraw the ROI?

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