New issue 322: USERPROFILE is not passed by default on Windows https://bitbucket.org/hpk42/tox/issues/322/userprofile-is-not-passed-by-default-on
André Caron: I just got bit by this strange issue. One of my Tox virtual environment creates a nested virtual environment which does not respect settings in `~/pip/pip.ini`. This is problematic because the nested environment needs to install packages from our corporate DevPI installation. I can "fix" this by adding `USERPROFILE` in `passenv`, but I find it strange that the default behavior breaks pip and it's really hard to diagnose this unless you can make educated guesses about pip internals.
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