Nick Coghlan added the comment:

Now that Brett has a substantial portion of the benchmark suite running on 
Py3k, we should see a bit more progress on the PyPy-inspired 
project (which should make it much easier to catch this kind of regression 
before it hits a production release).

In this case, as I noted in my earlier comment, I think the 3.3 changes to 
make_key broke an important single-argument fast path that the re module was 
previously relying on, thus the major degradation in performance on a cache 
hit. I haven't looked into setting up the benchmark suite on my own machine 
though, so we won't know for sure until either I get around to doing that, or 
someone with it already set up tries the change I suggested above.


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