Alan Yorinks added the comment:

Additional information:
When using another example from PyMata, 
examples/digital_analog_io/callback_digital_analog_io.py, by adding the line:
        if sys.platform == 'linux':
            # noinspection PyUnresolvedReferences
            self.arduino.nonblocking()
Allowed the program to run without much noticeable lag. This program is a lot 
less io intensive.

Also, setting the pyserial init option, writeTimeout, did not seem to affect 
performance when running either test program.

I have run cProfile and ran the output through pyprof2calltree for the 
polling_digital_analog_io.py example.

I am attaching the result of pyprof2calltree to a file called 3. I will provide 
a similar file for the run with python 2.7.8 in an addtional comment (I can't 
attach more than 1 file per comment).

----------
Added file: http://bugs.python.org/file37880/3

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