Raymond Hettinger added the comment:

If you have a chance, run a C profiler so we can see whether most of the time 
is being spent in an attribute lookup for the current property(itemgetter) 
approach versus your nt-indexer approach.  Without a profile, I have only my 
instincts that the overhead is a mix of indirections and function call overhead 
(both solveable by in-lining), and over-generalization for all 
PyObject_GetItem() (solvable by specialization to a tuple subclass), and 
variable length argument lists (solveable by using of PyTuple_New(1)).   

Ideally, I would like something that speeds-up broader swaths of the language 
and doesn't obfuscate the otherwise clean generated code.  ISTM that the C code 
for both property() and itemgetter() still have room to optimize the common 
case.

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Python tracker <rep...@bugs.python.org>
<http://bugs.python.org/issue23910>
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