eryksun added the comment: No, ctypes.Structure should use native endianness. So on a little-endian it's the same as ctypes.LittleEndianStructure, and on a big-endian system it's the same as ctypes.BigEndianStructure. ARM processors can work in either mode. IIRC, the Raspberry Pi is built as a little-endian system. Check sys.byteorder to be sure.
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