Antoine Pitrou <pit...@free.fr> added the comment:

Ok, I ran the benchmarks here (Ubuntu 16.04, Core i5-2500K, PGO and LTO 
disabled) and I don't get any consistent speedup, which is more in line with 
what I was expecting:
https://gist.github.com/pitrou/29eb7592fa1eae2be390f3bfa3db0a3a

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<https://bugs.python.org/issue32534>
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