Serhiy Storchaka <storchaka+cpyt...@gmail.com> added the comment:

CPU = Intel(R) Core(TM) i7-6700HQ CPU @ 2.60GHz
Ubuntu 18.04
Linux 4.15.0 x86_64
gcc 7.3.0

Performing the check in save() can have not insignificant overhead (especially 
after implementing the issue34141 optimization). It can be reduced if perform 
it when flush a frame (in protocol 4) or buffer to the file, or after writing 
significant amount of bytes into buffer.

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Python tracker <rep...@bugs.python.org>
<https://bugs.python.org/issue34128>
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