mattip <matti.pi...@gmail.com> added the comment:

It seems changing os.environ['PATH'] is a security risk and is not allowed for 
Windows Store apps. The suggestion in the NumPy issue is to:

- use AddDllDirectory, (which is as accessable as os.environ['PATH'] but is not 
considered a security risk so far), but this requires using 
SetDefaultDllDirectories which breaks other things

- put any dlls required for the c-extension pyd in the same directory which 
means scipy and numpy will be using duplicate and potentially different 
OpenBLAS dlls, and whoever imports first wins

- load all the required dlls via LoadLibrary, meaning NumPy will have to export 
a windows-only API to SciPy so the latter can know where the DLL is.

I am glad NumPy only has one DLL, and not a dozen like QT or wxPython. 

Is there a PEP that describes the overall design of windows directory layout or 
a design guide for package authors with best practices for additional dll 
dependencies?

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<https://bugs.python.org/issue35688>
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