Inada Naoki <songofaca...@gmail.com> added the comment:

I can not confirm performance regression in 3.8.0.

$ time ~/pyenv/versions/3.7.3/bin/python permutations2x2 --max_depth 6 | egrep 
"^# Total_Time" ; time ~/pyenv/versions/3.8.0/bin/python permutations2x2 
--max_depth 6 | egrep "^# Total_Time"
# Total_Time: 50.24

real    0m50.665s                                                               
                                                                                
                                                                                
                              user    0m49.729s
sys     0m4.354s
# Total_Time: 47.97

real    0m48.502s
user    0m47.380s
sys     0m4.506s

I suspect that this is a binary specific issue.

Would you try "perf record python ..."?

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<https://bugs.python.org/issue38477>
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