Nicolas Dessart <nicolas.dess...@gmail.com> added the comment:

As I said in the associated PR, the build is failing on macOS because ctypes 
uses an obsolete libffi version bundled into Modules/_ctypes/libffi_osx for 
this platform. This old version of libffi is missing ffi_prep_cif_var.

There is an open issue that propose to remove the bundled libffi for OSX.
https://bugs.python.org/issue28491

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versions:  -Python 2.7, Python 3.5, Python 3.6

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