Christian Heimes <li...@cheimes.de> added the comment:

My question from last year has not been answered yet. Is there any valid 
scientific research on the number of rounds or duration? I neither know nor do 
I understand how Django came up with the numbers. PyCA cryptography copied the 
numbers without questioning them.

Were does 250ms come from? 250ms at 100% CPU load sound way too costly for a 
website login and too fast for a password manager. For comparison Argon2's 
default runtime on my laptop is 50ms.

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<https://bugs.python.org/issue42982>
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