Hi Guido, Yes indeed, wrong list - I've forwarded this to the intended destination, biopython-dev, and we'll continue the discussion there: http://lists.open-bio.org/pipermail/biopython-dev/2013-April/010560.html
(It is nice to see Python getting used in all sorts of Google Summer of Code projects though - and I'm sure we're all keen to try and welcome and encourage new students to the different open source communities.) Thanks, Peter On Sat, Apr 27, 2013 at 6:36 PM, Guido van Rossum <gu...@python.org> wrote: > Sounds like this was accidentally CC'ed to python-dev. > > On Sat, Apr 27, 2013 at 10:23 AM, 阮铮 <rz1...@foxmail.com> wrote: >> Hi Eric and Peter, >> >> I'm preparing the proposal for the codon alignment project. Two things I may >> want to hear your advice. >> >> 1) In the biopython wiki page, you mentioned "model selection" in the >> Approach & Goals. I'm not sure if there are any advantages to use codon >> alignment for model selection. Could you give me some references? Another >> thing is that model selection involves estimation of tree topology as well >> as branch lengthes and parameters across many substitution models. Will it >> be too computationally intensive for a python implementation? >> >> 2) You also mentioned the "validation (testing for frame shift)". Is there a >> test for frame shift? Or I can simply detect it by comparing amino acid >> sequences and nucleotide sequences. >> >> Best, >> Zheng Ruan >> >> _______________________________________________ >> Python-Dev mailing list >> Python-Dev@python.org >> http://mail.python.org/mailman/listinfo/python-dev >> Unsubscribe: >> http://mail.python.org/mailman/options/python-dev/guido%40python.org >> > > > > -- > --Guido van Rossum (python.org/~guido) _______________________________________________ Python-Dev mailing list Python-Dev@python.org http://mail.python.org/mailman/listinfo/python-dev Unsubscribe: http://mail.python.org/mailman/options/python-dev/archive%40mail-archive.com