With respect to Pythran:

Pythran is "for a subset of the Python language, with a focus on scientific 
computing."  PysoniQ is not a subset of the Python language.  

Currently Pythran is for Python 2.7 and "has decent Python 3 support."  PysoniQ 
is Python 3.x only, and goes through the most recent release of CPython.  

"Pythran depends on a few Python modules and several C++ libraries" which you 
will need to install manually.  No installation is needed for PysoniQ.

Pythran also requires some code rewriting.  PysoniQ does not.  

With Pythran you also have to compile manually, but with PysoniQ that's not 
needed. 

That's a very brief summary of some of the differences between PysoniQ and 
Cython, Nutika and Pythran.  

Mark
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