Thanks to Jerry Hill above who helped. This worked:
from pywinauto.application import Application
app = Application()
app.start_(r'C:\temp\hallbig2.exe')
app.Form1.Edit6.TypeKeys(r'C:\temp\input\Ea39j.txt')
E_Value = ""
while (E_Value == ""):
app.Form1.Compute.Click()
E_Value = app.Form1.Edit8.WindowText()
print repr(E_Value)
app.Kill_()
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