I have used Grayson's book - purchased and read many years ago now though.

I am only an occasional GUI programmer, but have recently moved away from 
Tkinter and ttk towards wxPython - mainly because I am very dissatisfied with 
the lack of widgets to choose from. (new from 2.7 on) ttk supposedly added to 
the basic TkInter kit but is extremely difficult to work out due to lack of 
documentation i.e. I quickly wanted to use styles and finding some easy 
documentation that explained how all that worked was impossible - despite 
searching the Internet for hours (perhaps I was just unlucky? :-)).

For learning wxPython I am using "wxPython in Action" by Noel Rappin and Robin 
Dunn.

Neither book is about learning Python though - they are both aimed at users who 
have at least a basic Python background and want to learn about the particular 
GUI toolkit in question.

Even though I am on my first wxPython GUI, I am extremely happy that I made the 
switch - I am already using basic wxPython widgets that were just not available 
under TkInter/ttk, creating a much more intuitive interface (IMO :-)) for my 
users.

Best of luck in your choices,
Peter
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