Separation of concerns is not a question about language, but how your code is organised. Python is a general-purpose language and isn't restricted to certain programming domains. The restrictions are purely practical, such as performance and the availability of the runtime on various platforms.
There are many Python frameworks that could qualify as front end tools, including various attempts at running Python on the JS runtime in browsers. The pyodide project which runs Python and native code on webassembly in the browser, frameworks for desktop applications and even command line interfaces are all front end. -- https://mail.python.org/mailman/listinfo/python-list
