Ah.  I use Slackware for my non-work computing needs.  That, and a couple of 
OpenBSD machines.  This is a systemd related move, I assume.

We're pretty much a CentOS shop at my work, so I'm going with it regardless.  
I'll make it work.

> On Mar 4, 2017, at 12:56 AM, Tony White <[email protected]> wrote:
> 
> FYI - looking at Devuan, Slackware as a replacement for CentOS5.
> 
> best wishes
>   Tony White
> 
> 
>> On 4/03/2017 16:47, Sean P. Murphy wrote:
>> Happy to help, Tony.
>> 
>> On Mar 4, 2017, at 12:42 AM, Tony White <[email protected]> wrote:
>> 
>>> Hi,
>>>   Thank you you are both correct.
>>> It was indeed clamd causing the issue.
>>> As to finally upgrading to CentOS 6 or 7 well that is
>>> not going to happen. 
>>> 
>>>   Thanks again.
>>> 
>>> best wishes
>>>   Tony White
>>> 
>>> On 4/03/2017 16:00, Sean P. Murphy wrote:
>>>> Tony,
>>>> 
>>>> This is an issue with a signature in the daily clamav database update.  It 
>>>> affects servers running on CentOS 5 due to the fact that they have a 
>>>> version of pcre that clamav can't link to properly to form the database.  
>>>> CentOS 6 and 7 aren't affected.  Supposedly the clamav folks have built a 
>>>> version of daily that won't break mail delivery, but I don't know for 
>>>> sure.  If you turn off clamav in simcontrol and recompile qmail cab, then 
>>>> mail delivery will resume unaffected.  You won't have virus scanning on 
>>>> incoming mail, but at least delivery will work.
>>>> 
>>>> Check the clamav mailing list: lists.clamav.net/pipermail/clamav-users for 
>>>> a better explanation.
>>>> 
>>>> They won't support clamav 99.3 on pre-CentOS 6 installs, so looks like 
>>>> it's finally time to  
>>>> upgrade those old servers, eh?
>>>> 
>>>> On Mar 3, 2017, at 10:26 PM, Tony White <[email protected]> wrote:
>>>> 
>>>>> Hi folks,
>>>>>   This is Tony sorry to have to use a Yahoo acount but my mail server
>>>>> broke this morning at 8am.
>>>>>   Submission and SMTP servers are now responding to connections
>>>>> with this error...
>>>>> 
>>>>> qmail-smtpd: qq soft reject (mail server temporarily rejected message 
>>>>> (#4.3.0))
>>>>> 
>>>>> I have made no changes so I am at a loss to the issue. Clamd is at 100% on
>>>>> a single core might that be the issue?
>>>>> 
>>>>> TIA.
>>>>> 
>>>>> Tony
>>> 
> 

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