It's high time for a small, reproducible example. Don't say, "for example", *give* us an example in R.

That being said, something like

combined[!names(combined) %in% names(miceSample)]

might be a start...

Addi Wei wrote:
But "miceSample" has multiple columns...  For example if nvars=4, I have 4
columns of data to delete from "combined".

Specifically, I have 187 columns in "combined", and "miceSample" only has 4
columns.   So the new data frame should have 183 columns.

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