At the moment, there is no possibility of specifying the weights with the rma() 
function. While the main model fitting part could be easily adapted to 
incorporate user-specified weights, the problem comes in with all the 
additional statistics that can be computed based on a fitted model. How should 
the predict() function now work? What would be the definition of I^2 now? How 
would one generalize the influence and outlier statistics to that case? Just to 
give some examples.

Of course, I could leave out such things when the user has specified the 
weights, but then things also get confusing for the user. For example, it is 
already less than ideal that you can only use the trim and fill method with 
models that do not incorporate moderators. Nobody has (as of yet) generalized 
the trim and fill method to that case. But when there are too many "special 
cases", the package becomes unusable.

I did consider user-specified weights at one point, but it opened up so many 
cans of worms that I preferred to quickly put the lid pack on those cans. That 
item is written down in my to-do list, but to be honest, it is somewhere at the 
very end of that list.

If you are hesitant to combine the results from those two types of studies, 
what about simply using a moderator to distinguish the two groups?

Best,

Wolfgang

--   
Wolfgang Viechtbauer, Ph.D., Statistician   
Department of Psychiatry and Psychology   
School for Mental Health and Neuroscience   
Faculty of Health, Medicine, and Life Sciences   
Maastricht University, P.O. Box 616 (VIJV1)   
6200 MD Maastricht, The Netherlands   
+31 (43) 388-4170 | http://www.wvbauer.com   


> -----Original Message-----
> From: r-help-boun...@r-project.org [mailto:r-help-boun...@r-project.org]
> On Behalf Of Anke Stein
> Sent: Thursday, May 24, 2012 15:59
> To: r-help@r-project.org
> Subject: [R] package metafor: specify weights?
> 
> Dear R-experts,
> Dear Wolfgang,
> 
> Weighted model fitting in metafor uses the inverse of the study specific
> variances as weights.
> I am wondering if it is possible to specify different weights.
> 
> In my meta-analysis, there are two types of studies with (intrinsic)
> differences in their range of sample sizes (which are used to calculate
> the variances of Fisher's z).
> I would like to try normalizing the sample sizes within each set of the
> two study types and use these normalized sample sizes as weights.
> Would that be possible with rma()? So far, I only found the option
> "weighted = TRUE/FALSE", but no possibility to specify which weights
> should be used.
> 
> Many thanks in advance,
> Anke
> 
> 
> 
> 
> 
> 
> --
> __________________________________________________________
> Anke Stein (Dipl.-Biol.)
> 
> Biodiversity, Macroecology & Conservation Biogeography Head Prof. Dr.
> Holger Kreft Georg-August University of Göttingen Büsgenweg 2 | 37077
> Göttingen | Germany
> 
> phone +49(0)551-39-13761
> fax +49(0)551-39-3618
> ast...@uni-goettingen.de
> http://www.uni-goettingen.de/biodiversity
> 
> ______________________________________________
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> PLEASE do read the posting guide http://www.R-project.org/posting-
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