On 12/05/2008, at 4:52 AM, Federico Calboli wrote:

On 10 May 2008, at 07:36, Kingsford Jones wrote:
Federico,

I think you'll be more likely to receive the type of response you're
looking for if you formulate your question more clearly.  The
inclusion of "commented, minimal, self-contained, reproducible code"
(as is requested at the bottom of every email sent by r-help) is an
effective way to clarify the issues.  Also, when asking a question
about fitting a model it's helpful to describe the specific research
questions you want the model to answer.

<snip>

I apprecciate that my description of the *full* model is not 100% clear, but my main beef was another.

The main point of my question is, having a 3 way anova (or ancova, if you prefer), with *no* nesting, 2 fixed effects and 1 random effect, why is it so boneheaded difficult to specify a bog standard fully crossed model? I'm not talking about some rarified esoteric model here, we're talking about stuff tought in a first year Biology Stats course here[1].

Now, to avoid any chances of being misunderstood in my use of the words 'fully crossed model', what I mean is a simple

y ~ effect1 * effect2 * effect3

with effect3 being random (all all the jazz that comes from this fact). I fully apprecciate that the only reasonable F-tests would be for effect1, effect2 and effect1:effect2, but there is no way I can use lme to specify such simple thing without getting the *wrong* denDF. I need light on this topic and I'd say it's a general enough question not to need much more handholding than this.


There is only one random effect, so where does the crossing come from ? The fixed effects vary across blocks, but they are fixed so are just covariates. For this type of data the usual model in lme4 is y~fixed1+fixed2+1|group and for lme split into fixed and random parts.


Having said that, I did look at the mixed-effects mailing list before posting here, and it looks like it was *not* the right place to post anyway:

'This mailing list is primarily for useRs and programmeRs interested in *development* and beta-testing of the lme4 package.'

although the R-Me is now CC'd in this.

I fully apprecciate that R is developed for love, not money, and if I knew how to write an user friendly frontend for nlme and lme4 (and I knew how to actually get the model I want) I'd be pretty happy to do so and submit it as a library. In any case, I feel my complaint is pefectly valid, because specifying such basic model should ideally not such a chore, and I think the powers that be might actually find some use from user feedback.


The problems seems to be that you want lme to work in the same way as an ANOVA table and it doesn't. The secret with lme and lme4 is to think about the structure of the data and describe with an equation. Then each term in the equation corresponds to part of the model definition in R.


Once I have sorted how to specify such trivial model I'll face the horror of the nesting, in any case I attach a toy dataset I created especially to test how to specify the correct model (silly me).


I'm a bit lost with your data file, it has 4 covariates, which is more than enough for 2 fixed effects, assuming block is the grouping and y the outcome.

Ken

Best,

Federico Calboli

[1] So much bog standard that the Zar, IV ed, gives a nice table of how to compute the F-tests correctly, taking into account that one of the 3 effects is randon (I'll send the exact page and table number tomorrow, I don't have the book at home).

<testdat.txt>
--
Federico C. F. Calboli
Department of Epidemiology and Public Health
Imperial College, St. Mary's Campus
Norfolk Place, London W2 1PG

Tel +44 (0)20 75941602   Fax +44 (0)20 75943193

f.calboli [.a.t] imperial.ac.uk
f.calboli [.a.t] gmail.com



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