Hi

Try the following reference:

Comparison of Three Methods for Estimating the
Standard Error of the Area under the Curve in ROC
Analysis of Quantitative Data by Hajian-Tilaki and Hanley, Academic
Radiology, Vol 9, No 11, November 2002.

Below is a simple implementation that will return both the AUC and its
standard error (DeLong et al method). 

Hope this helps...

Pedro


#Input: yreal [-1,1]

auc <- function(yreal,forecasts){

        sizeT <-nrow(yreal)
        pos <- 0
        for(i in 1:sizeT){
                if(yreal[i]>0) {pos <- pos + 1}
        }
        neg <- sizeT-pos
        yrealpos <- vector(length=pos)
        yrealneg <- vector(length=neg)
        forepos  <- vector(length=pos)
        foreneg  <- vector(length=neg)
        
        controlpos <- 1
        controlneg <- 1
        for(i in 1:sizeT){
                if(yreal[i]>0) {
                        yrealpos[controlpos] <- yreal[i]
                        forepos[controlpos]  <- forecasts[i]
                        controlpos <- controlpos + 1            
                } else {
                        yrealneg[controlneg] <- yreal[i]
                        foreneg[controlneg] <- forecasts[i]
                        controlneg <- controlneg + 1
                }
        }
        oper <- 0
        for( i in 1:pos){
                for(j in 1:neg){
                        if(forepos[i] > foreneg[j]) {oper <- oper + 1}
                        if(forepos[i]==foreneg[j]) {oper <- oper + 0.50
} 
                }
        }

        area <- oper/(pos*neg)
        vpj <- vector(length=pos)
                vqk <- vector(length=neg)
                oper <- 0
                for(i in 1:pos){
                        for(j in 1:neg){
                                if(forepos[i] > foreneg[j]) {oper <-
oper + 1 
                                } else {if(forepos[i]==foreneg[j]) {oper
<- oper + 0.50 }} 
                        }
                        division <- oper/neg
                        resta <- (division-area)^2
                        vpj[i] <- resta
                        oper <- 0
                }
                oper  <- 0
                resta <- 0
                for(j in 1:neg){
                        for(i in 1:pos){
                                if(forepos[i] > foreneg[j]) {oper <-
oper + 1 
                                } else {if(forepos[i]==foreneg[j]) {oper
<- oper + 0.50 }} 
                        }
                        division <- oper/pos
                        resta <- (division-area)^2      
                        vqk[j] <- resta
                        oper   <- 0
                }
        vpj <- vpj/(pos*(pos-1))
        vqk <- vqk/(neg*(neg-1))
        var <- sum(vpj)+sum(vqk)
        s   <- sqrt(var)

        return(list(AUC=area, std=s))
}

-----Original Message-----
From: [EMAIL PROTECTED] [mailto:[EMAIL PROTECTED]
On Behalf Of Frank E Harrell Jr
Sent: Monday, September 08, 2008 8:22 AM
To: gallon li
Cc: r-help
Subject: Re: [R] ROC curve from logistic regression

gallon li wrote:
> I know how to compute the ROC curve and the empirical AUC from the
logistic
> regression after fitting the model.
> 
> But here is my question, how can I compute the standard error for the
AUC
> estimator resulting form logistic regression? The variance should be
more
> complicated than AUC based on known test results. Does anybody know a
> reference on this problem?
>

The rcorr.cens function in the Hmisc package will compute the std. error

of Somers' Dxy rank correlation.  Dxy = 2*(C-.5) where C is the ROC 
area.  This standard error does not include a variance component for the

uncertainty in the model (e.g., it does not penalize for the estimation 
of the regression coefficients if you are estimating the coefficients 
and assessing ROC area on the same sample).

The lrm function in the Design package fits binary and ordinal logistic 
regression models and reports C, Dxy, and other measures.

I haven't seen an example where drawing the ROC curve provides useful 
information that leads to correct actions.

Frank
-- 
Frank E Harrell Jr   Professor and Chair           School of Medicine
                      Department of Biostatistics   Vanderbilt
University

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