Jennifer Mollon wrote:
>
>
> The response is a measurement - the amount of DNA extracted during the
> experiment. There were 2 factors to be tested - one is the condition
> under which the experiment took place and the other is the type of DNA
> to be extracted. Each set of factors was replicated, so condition A
> and DNA type A were tested twice using the same input material.
> Finally, the whole experiment was repeated twice, but in one of the
> experiments there was not enough input material and one of the DNA
> types (call it type D) was not tested at all, but all other levels of
> that factor and the condition factor were tested. From this, I think:
> ....
>
This is a classical case for procedure lme in package nlme which is quite
robust for unbalanced designs. Arrange your data in the long form;
preferably use characters instead of numbers to describe the levels.
Check the book by Pinheiro/Bates for details; or, as a starter, the examples
in library/nlme/scripts.
Dieter
Condition DNA Run Amount
CondA DNAA Run1 33
CondA DNAB Run1 22
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