-- Dear R users,

I have data on around 2000 birds from 3 generations for which I know an individual's pedigree (i.e. the relationship it shares with other individuals e.g brother, uncle, mother) and also a pedigree based on foster-families, because half broods were removed from their nest of origin and placed in a foster parent's nest.

From this I want to model two types of random effects. The first are additive genetic effects (Va) and the variance-covariance matrix associated with these are nearly always positive-definite and will look something like the following:

 1   0   0  0.5   0
 0   1   0  0.5   0
 0   0   1   0    0
0.5 0.5  0   1   0.25
 0   0   0  0.25   1

The elements basically correspond to the proportion of genes shared by any two individuals.

The second matrix will model additive maternal effects (Vm) and the variance-covariance matrix associated with these effects will usually not be positive definite as shown below.

1   1    0    0   0.5
1   1    0    0    0
0   0    1    1    0
0   0    1    1    0
0.5 0    0    0    1

The elements here correspond to the proportion of genes shared by the (foster) parents of the two individuals. In this case 2 individuals raised in the same nest that fail to breed in subsequent years will have identical variance-covariance elements (row 3&4).

The structure of the random effects for the model will then be:


Va 0 0 Vm

or possibly,

   Va     Cov(a,m)
Cov(m,a)     Vm


I am quite new to both mixed effect models and R so would like to know if it is possible to specify specific variance covariance structures and whether non-positive-definite matrices can be used.


Many thanks

Jarrod Hadfield.

______________________________________________
[EMAIL PROTECTED] mailing list
https://www.stat.math.ethz.ch/mailman/listinfo/r-help

Reply via email to