On Thu, 05 Jun 2003 21:50:13 -0400
"Liaw, Andy" <[EMAIL PROTECTED]> wrote:

> Hi Frank,
> 
> > From: Frank E Harrell Jr [mailto:[EMAIL PROTECTED]
> 
> [snip]
> 
> > The anova method for ols fits 'works' when you penalize the 
> > model but there is some controversy over whether we should be 
> > testing biased coefficients.  Some believe that hypothesis 
> > tests should be done using the unpenalized model.  That 
> > brings up other ways to handle collinearity: test groups of 
> > variables in combination so they don't compete with each 
> > other, or collapse them into summary scores (e.g., principal 
> > components) before putting them in the model. 
> 
> I'm not clear about the last point.  Suppose three of the variables
> are nearly collinear.  Are you suggesting to replace the variables
> with the first one or two PCs, and drop the rest?  If so, doesn't
> that also lead to biased estimators?

Yes, it's another way to get biased estimators.  But many statisticians test these 
components in incomplete principal components regression using ordinary tests, to get 
tests for the whole group of coefficients these represent (under restrictions).  -Frank

> 
> Best,
> Andy
>  
> > ---
> > Frank E Harrell Jr              Prof. of Biostatistics & Statistics
> > Div. of Biostatistics & Epidem. Dept. of Health Evaluation Sciences
> > U. Virginia School of Medicine  
> > http://hesweb1.med.virginia.edu/biostat
> 
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---
Frank E Harrell Jr              Prof. of Biostatistics & Statistics
Div. of Biostatistics & Epidem. Dept. of Health Evaluation Sciences
U. Virginia School of Medicine  http://hesweb1.med.virginia.edu/biostat

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