Dear RenE,

Can you explain a bit more how you derive your T.SPart? Thatīs what I think is the tricky part of your analysis.

I would suggest you should try to end up with something like this:

model1<-aov(SR~WasSick*Time+Error(Subject/Time)
model2<-aov(SR~SC*Time+Error(Subject/Time)

This way it would be like a repeated measures ANOVA, where WasSick (or SC) are the primary covariates, and Time is nested within Subject.

I think the correct specification of "time" is crucial for the whole analysis. Itīs like in a split-plot ANOVA, where finding the appropriate codings for plots of different sizes can sometimes take a very long time.

Regards,
Christoph


0) Subject, the subject identifier 1) physiological recordings, say SR (skin resistance): time series 2) a SessionPart variable (parts R1 and R2, separated in time by a pause) 3) time, T.SPart: normalised per subject and per SessionPart, so twice 0..1 4) a subjective sickness estimate (SC): time series 5) a per-subject classification: WasSick or not (available as a time series, but constant in time of course)





RenE J.V. Bertin wrote:

On Sun, 10 Oct 2004 19:55:41 +0200, "RenE J.V. Bertin" <[EMAIL PROTECTED]> wrote 
regarding "Re:
[R] some help interpreting ANOVA results, please?"

I'm would like to come back to a question I posted quite a while ago, 
concerning the analysis of data of an ongoing experiment. I have, for a given 
number of subjects:
0) Subject, the subject identifier
1) physiological recordings, say SR (skin resistance): time series
2) a SessionPart variable (parts R1 and R2, separated in time by a pause)
3) time, T.SPart: normalised per subject and per SessionPart, so twice 0..1
4) a subjective sickness estimate (SC): time series
5) a per-subject classification: WasSick or not (available as a time series, 
but constant in time of course)

I would like to make statements on whether or not sickness (measured by 4 or 5) can be deduced from the physiological recordings, e.g. something like


aov( SR ~ WasSick * T.SPart )



expecting a significant effect of time (sickness building up), of WasSick, and a significant interaction showing that the effect is stronger (or only significant) in the WasSick=TRUE subjects. A simple t.test(SR~WasSick) gives a significant difference, as well as t.test( SR~ (T.SPart>=0.5) ) .

The problem I'm having is that WasSick (and SC) are not independent variables 
properly speaking. So I cannot do



aov( SR ~ WasSick * T.SPart + Error(Subject/WasSick*T.SPart) )



R would remove WasSick from the Error term, and do the analysis without it, giving a significant T.SPart effect and WasSick:T.SPart interaction (?), both listed under Error: Subject:T.SPart :
Error: Subject:T.SPart
Df Sum Sq Mean Sq F value Pr(>F) T.SPart 5 318.2 63.6 8.336 7.46e-07 ***
WasSick:T.SPart 5 125.5 25.1 3.289 0.0079 ** Residuals 129 984.9 7.6


There is no trace of a WasSick effect other than in that interaction (of which 
I'm not sure it is truly one).



I have 2 questions at this point:

A) I think one could assimilate WasSick to a grouping variable (like in a clinical stdudy), forgetting it is actually an observation on the subjects. In that case, I could do


aov( SR ~ WasSick * T.SPart )


which gives me the expected two significant main effects and the significant 
interaction (which agrees with visual inspection of the data).
Is this an acceptable approach/model?

B) Should I contine putting the Subject id in an Error term, e.g.


aov( SR ~ WasSick + Error(Subject) )


WithOUT this error term, that anova gives a significant effect, confirming the 
t.test mentioned above. If I include the error term, the effect is no longer 
significant.
Is that because the model does not make sense, rather because my data are so non-normal 
that a t.test cannot be used? (?Error has a similar model, and calls it "not 
particularly sensible statistically".)


I would really appreciate some more constructive comments! Thanks, RenE Bertin

PS: I must add that it has been suggested to try lme. I went over what docs I 
have (help and MASS 4), but these are far to specialistic for me, so I haven't 
gotten anywhere in that direction :(

______________________________________________
R-help@stat.math.ethz.ch mailing list
https://stat.ethz.ch/mailman/listinfo/r-help
PLEASE do read the posting guide! http://www.R-project.org/posting-guide.html




______________________________________________ R-help@stat.math.ethz.ch mailing list https://stat.ethz.ch/mailman/listinfo/r-help PLEASE do read the posting guide! http://www.R-project.org/posting-guide.html

Reply via email to