In connection with calculating Monte Carlo p-values based on sampled data sets: 
The calculations involve something like
   update(lmer.model, data=newdata)
where newdata is a simulated dataset comming from simulate(lmer.model). I guess 
the update could be faster if one could supply the update function with the 
parameter estimates from the original fit of the lmer.model as starting values. 
Is this possible to achieve??
Best
Søren

________________________________

Fra: [EMAIL PROTECTED] på vegne af Peter Dalgaard
Sendt: lø 28-01-2006 01:12
Til: Douglas Bates
Cc: Søren Højsgaard; [email protected]
Emne: Re: [R] how calculation degrees freedom



Douglas Bates <[EMAIL PROTECTED]> writes:


> > Of course, Monte Carlo p-values have their problems, but the world
> > is not perfect....
>
> Another approach is to use mcmcsamp to derive a sample from the
> posterior distribution of the parameters using Markov Chain Monte
> Carlo sampling.  If you are interested in intervals rather than
> p-values the HPDinterval function from the coda package can create
> those.
>

We (Søren and I) actually had a look at that, and it seems not to
solve the problem. Rather, mcmcsamp tends to reproduce the Wald style
inference (infinite DF) if you use a suitably vague prior.

It's a bit hard to understand clearly, but I think the crux is that
any Bayes inference only depends on data through the likelihood
function. The distribution of the likelihood never enters (the
hardcore Bayesian of course won't care). However, the nature of DF
corrections is that the LRT does not have its asymptotic distribution,
and mcmc has no way of picking that up.


--
   O__  ---- Peter Dalgaard             Øster Farimagsgade 5, Entr.B
  c/ /'_ --- Dept. of Biostatistics     PO Box 2099, 1014 Cph. K
 (*) \(*) -- University of Copenhagen   Denmark          Ph:  (+45) 35327918
~~~~~~~~~~ - ([EMAIL PROTECTED])                  FAX: (+45) 35327907

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