Please forgive a rather naïve question... 

Could someone please give a quick explanation for the differences in conf 
intervals achieved via confint.glm (based on profile liklihoods) and the 
intervals achieved using the Design library.

For example, the intervals in the following two outputs are different.

library(Design)
x = rnorm(100)
y = gl(2,50)
d = data.frame(x = x, y = y)
dd = datadist(d); options(datadist = 'dd')
m1 = lrm(y~x, data = d)
summary(m1)

m2 = glm(y~x, family = binomial, data = d)
confint(m2)

I have spent time trying to figure this out via archives, but have not had much 
luck.

Regards

Stephen

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