On Wed, 2007-03-28 at 10:49 -0500, Douglas Bates wrote:
> On 3/28/07, Marc Schwartz <[EMAIL PROTECTED]> wrote:
> > On Wed, 2007-03-28 at 02:42 -0700, francogrex wrote:
> > > Does anyone know of an R package that is equivalent of S+SeqTrial for
> > > analysis of clinical trials using group sequential methods? Thanks.
> >
> > I don't know that there are fully functional equivalents, but you might
> > want to look at the following:
> >
> > 1. The GroupSeq package on CRAN:
> >
> >   http://cran.r-project.org/src/contrib/Descriptions/GroupSeq.html
> >
> >
> > 2. The ldBands() function in Frank Harrell's Hmisc package on CRAN:
> >
> >   http://biostat.mc.vanderbilt.edu/s/Hmisc/html/ldBands.html
> >
> > This also requires the ld98 executable, which is available from:
> >
> >   http://www.biostat.wisc.edu/landemets/
> 
> There is also the ldbounds package on CRAN for calculating Lan-DeMets
> boundaries.  It was prepared by students working with Dave DeMets and
> does not require the ld98 executable.


Thanks Doug, I missed that one.

Regards,

Marc

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